GIANT-CELL TUMOR OF BONE: TREATMENT OPTIONS AND ROLE OF DENOSUMAB

Giant-cell tumor of bone: treatment options and role of denosumab

Arun S Singh,1 Neal S Chawla,2 Sant P Chawla2 1Sarcoma Service, Division of Hematology/Oncology, University of California, Los Angeles, 2Sarcoma Oncology Center, Santa Monica, CA, USA Abstract: Giant-cell tumor of bone is a rare, locally aggressive tumor that typically occurs in underwater treasures sunken medallion the bones of skeletally mature y

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Taxes on money laundering as a source of state budget revenue

Money laundering is a phenomenon that needs to be considered from a multi-faceted perspective.Currently, legislation condemns behaviors that fulfill the elements of the money laundering offense, penalized by Polish criminal law.Additionally, the AML (Anti-Money Laundering) Act introduces sanctions that burden specific institutions due to their fail

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Examining heterogeneity of stromal cells in tumor microenvironment based on pan-cancer single-cell RNA sequencing data

Tumor tissues contain both tumor and non-tumor cells, which include infiltrated immune cells and stromal cells, collectively called the tumor microenvironment (TME).Single-cell cubs foam finger RNA sequencing (scRNAseq) enables the examination of heterogeneity of tumor cells and TME.In this review, we examined scRNAseq datasets for multiple cancer

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Assessing the Likelihood of High Pathogenicity Avian Influenza Incursion Into the Gamebird Sector in Great Britain via Designated Hatcheries

The outbreaks of High Pathogenicity Avian Influenza (HPAI) in the United Kingdom in 2017 and 2021 had a substantial impact on the gamebird industry and highlighted to policymakers the importance of existing knowledge gaps for effective disease control.Despite the size of the industry, the impact of HPAI on the gamebird industry is not well-understo

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